| Cheat Code | Description |
| DNKROZ | God Mode |
| DNSTUFF | All weapons, ammo, and key cards |
| DNWEAPONS | All weapons |
| DNITEMS | All items and key cards |
| DNKEYS | All Key cards |
| DNCLIP | No Clipping Mode |
| DNSHOWMAP | Full Map |
| DNHYPER | Steroids |
| DNUNLOCK | Toggles all Locks |
| DNSKILL# | Changes skill to Level # |
| DNSCOTTYell | Level Warp (where e=episode # and ll=level #) |
| DNVIEW | Chase plane view |
| DNMONSTERS | Monsters will disappear as soon as they see Duke |
| DNCASHMAN | Makes Duke throw money when you press the spacebar |
| DNRATE | Displays frame rate |
| DNCOORDS | Displays current coordinates |
| DNDEBUG | Displays debugging info |
| DNTODD | Displays message: Register Cosmo Today! |
| DNBETA | Displays message: Pirates Suck! |
| DNALLEN | Displays message: Buy Major Stryker |